| Buildings of Local Significance |
Address |
| Adams--Crocker--Fish House | 449 Willow St. |
| Ames, Josiah A., House | 145 Bridge St. |
| Ancient Burying Ground | Phinney's Ln. |
| Baker, Benjamin, Jr., House | 1579 Hyannis Rd. |
| Baker, Capt. Seth, Jr., House | 35 Main St. |
| Baxter, Charles L., House | 77 Main St. |
| Baxter, Shubael, House | 9 E. Bay Rd. |
| Bearse, Capt. Oliver, House | 31 Pearl St. |
| Blish--Garret House | 350 Plum St. |
| Building at 237--239 Main Street | 237--239 Main St. |
| Building at 600 Main Street | 600 Main St. |
| Building at 606 Main Street | 606 Main St. |
| Building at 614 Main Street | 614 Main St. |
| Campbell, Collen C., House | 599 Main St. |
| Canary--Hartnett House | 113 Winter St. |
| Centerville Historic District, Barnstable, Massachusetts | Main St. |
| Chase, Lemuel B., House | 340 Scudder Ave. |
| Codman, Col. Charles, Estate | 43 Ocean View Ave. |
| Cotuit Historic District | Main St., Lowell & Ocean View Aves. bounded by Osterville Harbor, Nantucket Sound, & Popponessett Bay |
| Craigville Historic District | Centerville Harbor, Nantucket Sound, Red Lily Pond, and Lake Elizabeth |
| Crocker, Ebenezer, Jr., House | 49 Putnam Ave. |
| Crosby, Daniel, House | 18 Bay St. |
| Crosby House | 33 Pine St. |
| Fuller House, Barnstable, Massachusetts | Parker Rd. |
| Gifford Farm | 261 Cotuit Rd. |
| Gleason, Dr. Edward Francis, House | 88 Lewis Bay Rd. |
| Gray, Capt. Thomas, House | 14 Main St. |
| Hallett, Capt. William, House | 570 Main St. |
| Hallett, Seth, House | 110 Main St. |
| Harlow Homestead | 391 Main St. |
| Hinckley, Capt. Joseph, House | 142 Old Stage Rd. |
| Hinckley, Nymphus, House | 38 Bay St. |
| Hinckley, S. Alexander, House | 151 Pine St. |
| Hinckley Homestead | 1740 S. County Rd. |
| Isham, Herman, House | 1322 Main St. |
| Liberty Hall, Barnstable, Massachusetts | Main St. |
| Lincoln House Club | 135 Bridge St. |
| Lovell, Capt. George, House | 8 E. Bay Rd. |
| Lovell, Nehemiah, House | 691 Main St. |
| Marstons Mills Hearse House and Cemetery | MA 149 |
| Merrill Estate | 1874 S. County Rd. |
| Methodist Church, Barnstable, Massachusetts | Main St. |
| Mill Way Historic District | Mill Way Rd. |
| Municipal Group Historic District | Roughly bounded by Main, Municipal Bldgs., South, and Pearl Sts. |
| Old King's Highway Historic District | Old King's Highway between Sandwich town line on the West to Yarmouth town line on the East |
| Osterville Baptist Church | Main St. |
| Phinney, William and Jane, House | 555 Phinney's Ln. |
| Pleasant--School Street Historic District | Roughly bounded by Main, School, South, and Pleasant Sts. |
| Rhodehouse, Nelson, House | 131 Main St. |
| Richardson, John, House, Barnstable, Massachusetts | 242 Phinney's Ln. |
| Robbins, Joseph, House | 12 Bay St. |
| Round House | 971 W. Main St. |
| Sampson's Folly--Josiah Sampson House | 40 Old King's Rd. |
| Santuit Historic District | MA 28 |
| Santuit Post Office | Main St. |
| Smith, Matthias, House | 375 Cedar St. |
| Whitman, Josiah B., House | 210 Maple St. |
| Wianno Historic District | Roughly E. Bay Rd., Wianno and Sea View Aves. between Nantucket Sound and Crystal Lake |